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Haemostasis is a complex process that helps to keep the blood in a fluid state and prevent blood loss at the site of injury. While the intact endothelium of blood vessels has an anti-thrombogenic function that prevents blood coagulation, in the case of vessel wall damage, the exposed sub-endothelial components initiate the formation of a clot that will stop blood loss.
- Body Fluid
Body fluid cell counts – how to perform and interpret the results
This SEED article is meant to explain the findings focused on cell count and differentiation for pleural, ascitic, cerebrospinal and synovial fluid as well as for CAPD. Traditionally, body fluid counts are performed by manual counting under a microscope using a haemocytometer, but laboratories now have the option of automating their manual processes using automated haematology or urinalysis analysers. This SEED summarises the advantages and disadvantages of haemocytometry and Sysmex analysers and explains briefly the XN-BF mode.
- Artykuły Xtra
Counting of highly fluorescent lymphocytes (HFLC) as antibody-producing plasma cells on XE-5000
Besides the IG there is a distinct separation of an abnormal cell population with high fluorescence intensity above the monocyte and lymphocyte region. Highly fluorescent lymphocyte cells (HFLC) are observed in the DIFF channel of the Sysmex XE-series haematology analysers in an area of high fluorescence intensity.
- Diagnostic Perspectives
Fighting for fair competition: blood doping – a persistent challenge and smart approaches to detect it
Doping with blood, erythropoietin or related substances is an unfair practice in sports and is performed to obtain an advantage over competing athletes. Doping control has made great progress in detecting the use of forbidden substances by employing completely new strategies that no longer rely on the detection of the banned substance itself. What is measured instead are the changes that forbidden doping practice has on haematological parameters.